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Alternatives depend on the clinical target

Mechanisms of Collagen Synthesis The collagen synthesis mechanisms involve several key pathways: MAPK/ERK Pathway Activation This pathway upregulates collagen gene expression and promotes fibroblast proliferation, creating the cellular foundation for tissue repair

Methods Network-based identification of natural products Construction of the AD-related pathway-gene network In this study, we aimed to screen AD-related pathways from three perspectives: Most Studied Pathways (pathways with the most literature on AD), Gene-Associated Pathways (derived from AD-associated gene enrichment analysis), and Popular Pathways (pathways showing an increasing trend in the literature)

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